Gabriele Multhoff Selected Research

Heat-Shock Proteins (Heat-Shock Protein)

1/2022	A Low Membrane Hsp70 Expression in Tumor Cells With Impaired Lactate Metabolism Mediates Radiosensitization by NVP-AUY922.
7/2021	Targeting Cancer Metabolism Breaks Radioresistance by Impairing the Stress Response.
1/2021	Role of Heat Shock Proteins in Immune Modulation in Malaria.
1/2020	Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets.
10/2019	Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors.
1/2019	Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922.
1/2019	Membrane Hsp70-supported cell-to-cell connections via tunneling nanotubes revealed by live-cell STED nanoscopy.
1/2019	Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70-Positive Tumors for Multimodal Cancer Theranostics.
1/2018	Membrane heat shock protein 70: a theranostic target for cancer therapy.
1/2017	Dynamics of Heat Shock Protein 70 Serum Levels As a Predictor of Clinical Response in Non-Small-Cell Lung Cancer and Correlation with the Hypoxia-Related Marker Osteopontin.

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Gabriele Multhoff Research Topics

Disease

131	Neoplasms (Cancer) 01/2022 - 10/2002
16	Hypoxia (Hypoxemia) 01/2021 - 08/2009
14	Neoplasm Metastasis (Metastasis) 12/2021 - 04/2003
10	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 11/2013
8	Squamous Cell Carcinoma of Head and Neck 07/2021 - 06/2014
8	Inflammation (Inflammations) 01/2021 - 01/2011
7	Hyperthermia 01/2021 - 05/2009
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020 - 06/2004
7	Carcinoma (Carcinomatosis) 01/2019 - 06/2005
6	Melanoma (Melanoma, Malignant) 01/2022 - 04/2003
5	Glioma (Gliomas) 01/2021 - 12/2015
5	Breast Neoplasms (Breast Cancer) 01/2020 - 01/2012
5	Adenocarcinoma 01/2018 - 05/2004
5	Carcinogenesis 01/2014 - 01/2011
4	Head and Neck Neoplasms (Head and Neck Cancer) 07/2021 - 11/2003
4	Acidosis 01/2021 - 01/2017
4	Lung Neoplasms (Lung Cancer) 01/2020 - 06/2004
3	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 06/2004
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 02/2010
3	Brain Neoplasms (Brain Tumor) 01/2018 - 12/2015
3	Leukemia 01/2016 - 04/2008
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2012 - 05/2006
3	Necrosis 11/2009 - 11/2002
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 06/2013
2	Cardiotoxicity 12/2021 - 01/2021
2	Malaria 01/2021 - 01/2012
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2020 - 04/2019
2	Hepatocellular Carcinoma (Hepatoma) 10/2019 - 01/2014

Drug/Important Bio-Agent (IBA)

44	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2022 - 10/2002
33	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022 - 05/2004
26	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2003
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2014
15	Peptides (Polypeptides)IBA 01/2022 - 01/2005
11	LipidsIBA 12/2021 - 01/2005
11	Monoclonal AntibodiesIBA 07/2021 - 04/2003
10	CytokinesIBA 01/2022 - 01/2008
9	Granzymes (Granzyme)IBA 12/2021 - 10/2003
9	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 11/2002
8	Pharmaceutical PreparationsIBA 01/2022 - 02/2010
8	Interleukin-2 (IL2)IBA 01/2015 - 10/2002
7	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 01/2017
6	5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA 01/2022 - 01/2012
6	AntigensIBA 01/2022 - 01/2005
6	LigandsIBA 12/2021 - 10/2007
5	PerforinIBA 12/2021 - 10/2003
5	Biological ProductsIBA 10/2021 - 05/2004
5	GoldIBA 10/2021 - 01/2015
5	Oxygen (Dioxygen)IBA 01/2021 - 01/2018
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 02/2010
5	micaIBA 01/2020 - 10/2007
5	SuspensionsIBA 01/2015 - 11/2003
4	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2016
4	InterleukinsIBA 01/2022 - 10/2002
4	Transcription Factors (Transcription Factor)IBA 12/2021 - 01/2011
4	ChemokinesIBA 12/2021 - 01/2016
4	Protons (Proton)IBA 01/2021 - 09/2012
4	Adenosine Triphosphate (ATP)IBA 01/2021 - 01/2014
4	CholesterolIBA 01/2021 - 01/2011
4	MicroRNAs (MicroRNA)IBA 01/2021 - 11/2013
4	AntibodiesIBA 01/2019 - 05/2011
4	EpitopesIBA 11/2018 - 04/2010
3	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2020
3	EnzymesIBA 12/2021 - 11/2012
3	Pyruvic Acid (Pyruvate)IBA 07/2021 - 01/2021
3	NucleotidesIBA 01/2021 - 05/2016
3	Amino Acids FDA Link 01/2021 - 01/2011
3	sodium-iodide symporter (sodium iodide symporter)IBA 01/2021 - 11/2018
3	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2016
3	Small Interfering RNA (siRNA)IBA 10/2020 - 02/2010
3	SurvivinIBA 10/2020 - 11/2013
3	PhosphatidylserinesIBA 01/2020 - 08/2009
3	Adenosine (Adenocard)FDA LinkGeneric 01/2020 - 01/2017
3	Messenger RNA (mRNA)IBA 11/2018 - 01/2012
3	IonsIBA 01/2017 - 01/2012
3	Immunoglobulin G (IgG)IBA 01/2015 - 01/2011
3	Indicators and Reagents (Reagents)IBA 12/2014 - 04/2008
3	Interleukin-1 (Interleukin 1)IBA 11/2012 - 01/2011
2	Protein Isoforms (Isoforms)IBA 01/2022 - 02/2016
2	PPAR alphaIBA 12/2021 - 06/2013
2	Death Domain ReceptorsIBA 12/2021 - 01/2016
2	GlycosphingolipidsIBA 07/2021 - 04/2008
2	Tumor Biomarkers (Tumor Markers)IBA 07/2021 - 01/2018
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2020
2	SirtuinsIBA 01/2021 - 01/2021
2	HexosaminesIBA 01/2021 - 01/2021
2	AfatinibIBA 01/2021 - 01/2016
2	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2020 - 05/2016
2	Epithelial Cell Adhesion MoleculeIBA 01/2020 - 01/2018
2	Molecular Chaperones (Chaperone, Molecular)IBA 01/2020 - 10/2019
2	Serine Proteases (Serine Protease)IBA 01/2019 - 08/2011
2	Fluorescein (Funduscein)FDA LinkGeneric 11/2018 - 01/2014

Therapy/Procedure

49	Therapeutics 01/2022 - 05/2004
29	Radiotherapy 10/2021 - 01/2012
10	Precision Medicine 12/2021 - 01/2014
9	Immunotherapy 01/2022 - 05/2004
8	Chemoradiotherapy 07/2021 - 01/2015
6	Drug Therapy (Chemotherapy) 12/2021 - 01/2008
3	Aftercare (After-Treatment) 01/2018 - 05/2004
2	Intravenous Administration 11/2021 - 12/2014
2	Adjuvant Chemotherapy 05/2019 - 01/2016